IVNS1ABP

Across TCGA patient cohorts, IVNS1ABP mutation is significantly associated with the RNA expression of many other genes, with 4,321 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IVNS1ABP-associated genes across cancer lineages are RNASEH1P2, MIR4797, and OR5AN1. Each is linked with IVNS1ABP in more than 2 cancer types. Because this analysis shows association rather than direction, both IVNS1ABP-to-partner and partner-to-IVNS1ABP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNASEH1P2 grouped by IVNS1ABP-low versus IVNS1ABP-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IVNS1ABP→partner) and Y-score (partner→IVNS1ABP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNASEH1P2 →	+0.093	+3.953	.007	.003	3	3
READ	MIR4797 →	+0.819	+5.054	<.001	.001	3	3
HNSC	OR5AN1 →	+0.021	+4.468	<.001	.006	3	3
UCEC	C9orf85 →	+0.302	+1.686	.001	.001	3	2
UCEC	RNF25 →	+0.321	+2.857	<.001	<.001	3	2
UCEC	PGGT1B →	+0.310	+1.436	.009	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,321 associations by consensus.

RNASEH1P2 by IVNS1ABP expression — CESC

Explore this box plot interactively →