IVNS1ABP

Across TCGA cell cohorts, IVNS1ABP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,609 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IVNS1ABP-associated GO terms across cancer lineages are Negative regulation of gene expression, epigenetic, Regulation of RNA export from nucleus, and Positive regulation of double-strand break repair. Each is linked with IVNS1ABP in more than 12 cancer types. Because this analysis shows association rather than direction, both IVNS1ABP-to-partner and partner-to-IVNS1ABP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of gene expression, epigenetic grouped by IVNS1ABP-low versus IVNS1ABP-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IVNS1ABP→partner) and Y-score (partner→IVNS1ABP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Negative regulation of gene expression, epigenetic →	+0.071	+1.371	<.001	<.001	3	13
LUNG_SCLC	Regulation of RNA export from nucleus →	+0.144	+1.319	<.001	<.001	3	13
BONE	Positive regulation of double-strand break repair →	+0.088	+1.897	<.001	<.001	3	12
BONE	Positive regulation of DNA metabolic process →	+0.085	+1.595	<.001	.001	3	12
LUNG_SCLC	Heterochromatin formation →	+0.072	+1.130	<.001	<.001	3	11
LUNG_SCLC	Regulation of alternative mRNA splicing, via spliceosome →	+0.129	+1.584	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,609 associations by consensus.

Negative regulation of gene expression, epigenetic by IVNS1ABP expression — LUNG_SCLC

Explore this box plot interactively →