IVNS1ABP

Across TCGA cell cohorts, IVNS1ABP mutation is significantly associated with the drug of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IVNS1ABP-associated genes across cancer lineages are 5-Fluorouracil, KU-60019, and AGI-6780. Each is linked with IVNS1ABP in more than 1 cancer types. Because this analysis shows association rather than direction, both IVNS1ABP-to-partner and partner-to-IVNS1ABP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 5-Fluorouracil grouped by IVNS1ABP-low versus IVNS1ABP-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IVNS1ABP→partner) and Y-score (partner→IVNS1ABP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	5-Fluorouracil →	+0.527	+3.184	.045	.007	3	1
LARGE_INTESTINE	KU-60019 →	+0.505	+2.710	.011	.027	3	1
LARGE_INTESTINE	AGI-6780 →	+0.358	+3.061	.041	.010	3	1
LARGE_INTESTINE	GSK626616AC →	+0.307	+2.710	.034	.027	3	1
LARGE_INTESTINE	Ispinesib Mesylate →	+0.723	+3.067	.013	.009	3	1
LARGE_INTESTINE	GSK690693 →	+0.598	+2.791	.008	.028	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

5-Fluorouracil by IVNS1ABP expression — LARGE_INTESTINE

Explore this box plot interactively →