ITPRID2

Across TCGA cell cohorts, ITPRID2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,771 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ITPRID2-associated GO terms across cancer lineages are Cellular response to environmental stimulus, Negative regulation of actin filament depolymerization, and Regulation of cellular component size. Each is linked with ITPRID2 in more than 11 cancer types. Because this analysis shows association rather than direction, both ITPRID2-to-partner and partner-to-ITPRID2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to environmental stimulus grouped by ITPRID2-low versus ITPRID2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ITPRID2→partner) and Y-score (partner→ITPRID2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cellular response to environmental stimulus →	+0.051	+1.224	<.001	<.001	3	12
BONE	Negative regulation of actin filament depolymerization →	+0.182	+0.810	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Regulation of cellular component size →	+0.054	+0.795	.005	.004	3	12
UPPER_AERODIGESTIVE_TRACT	Cellular response to abiotic stimulus →	+0.051	+1.224	<.001	<.001	3	12
PANCREAS	Regulation of actin filament length →	+0.096	+1.134	.002	.004	3	11
LUNG_NSCLC_LUAD	Regulation of actin filament polymerization →	+0.080	+0.784	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,771 associations by consensus.

Cellular response to environmental stimulus by ITPRID2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →