ITPRID2

Across TCGA cell cohorts, ITPRID2 mutation is significantly associated with the drug of many other genes, with 40 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ITPRID2-associated genes across cancer lineages are AZD6094, N22899-6-C1, and UNC1215. Each is linked with ITPRID2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ITPRID2-to-partner and partner-to-ITPRID2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AZD6094 grouped by ITPRID2-low versus ITPRID2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITPRID2→partner) and Y-score (partner→ITPRID2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	AZD6094 →	+0.158	+2.404	.019	.018	3	3
BLOOD_Leukemia	N22899-6-C1 →	+0.345	+3.321	.001	.006	3	2
BLOOD_Leukemia	UNC1215 →	+0.129	+2.866	.043	.023	3	2
LARGE_INTESTINE	Lenalidomide →	+0.351	+2.684	.014	.035	3	1
LARGE_INTESTINE	Cetuximab →	+0.490	+2.655	.047	.044	3	1
LARGE_INTESTINE	AZD7969 →	+0.577	+2.871	.006	.021	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

AZD6094 by ITPRID2 expression — BLOOD_Leukemia

Explore this box plot interactively →