ITPR1

Across TCGA patient cohorts, ITPR1 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,818 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ITPR1-associated proteins across cancer lineages are ITPR1_S1598, SORBS3, and SYNPO2. Each is linked with ITPR1 in more than 8 cancer types. Because this analysis shows association rather than direction, both ITPR1-to-partner and partner-to-ITPR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITPR1 versus ITPR1_S1598 in UCEC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ITPR1→partner) and Y-score (partner→ITPR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ITPR1_S1598 →	+0.756	+0.691	<.001	<.001	3	9
LUAD	SORBS3 →	+0.402	+0.696	<.001	<.001	3	7
HNSC	SYNPO2 →	+0.597	+0.381	<.001	<.001	3	7
HNSC	COL14A1 →	+0.827	+0.521	<.001	<.001	3	7
BRCA	AKAP12_S612 →	+0.865	+1.153	<.001	<.001	3	7
UCEC	GEM_S23 →	+1.065	+0.963	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,818 associations by consensus.

ITPR1 vs ITPR1_S1598 — UCEC

Explore this scatter interactively →