ITPKB

Across TCGA patient cohorts, ITPKB RNA expression is significantly associated with the protein abundance of many other proteins, with 14,051 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ITPKB-associated proteins across cancer lineages are ITPKB_S280, ITPKB_S43, and ITPKB_T33. Each is linked with ITPKB in more than 5 cancer types. Because this analysis shows association rather than direction, both ITPKB-to-partner and partner-to-ITPKB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITPKB versus ITPKB_S280 in LUAD, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ITPKB→partner) and Y-score (partner→ITPKB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ITPKB_S280 →	+0.992	+0.895	<.001	<.001	3	6
LSCC	ITPKB_S43 →	+0.559	+0.751	<.001	<.001	3	6
BRCA	ITPKB_T33 →	+0.569	+0.628	<.001	<.001	3	6
UCEC	GATAD2B →	+0.258	+0.770	<.001	<.001	3	5
HNSC	PARP1 →	+0.411	+0.620	<.001	<.001	3	4
HNSC	PGAM1_S31 →	-0.696	-0.752	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,051 associations by consensus.

ITPKB vs ITPKB_S280 — LUAD

Explore this scatter interactively →