ITPKB

Across TCGA patient cohorts, ITPKB protein abundance is significantly associated with the RNA expression of many other genes, with 11,437 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ITPKB-associated genes across cancer lineages are RGMA, ITPKB-AS1, and CASQ2. Each is linked with ITPKB in more than 5 cancer types. Because this analysis shows association rather than direction, both ITPKB-to-partner and partner-to-ITPKB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITPKB versus RGMA in LSCC, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITPKB→partner) and Y-score (partner→ITPKB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RGMA →	+1.074	+0.486	<.001	<.001	3	6
GBM	ITPKB-AS1 →	+0.831	+0.398	<.001	<.001	3	6
COAD	CASQ2 →	+1.654	+0.462	<.001	<.001	3	5
GBM	RASL12 →	+1.030	+0.395	<.001	<.001	3	5
UCEC	DCHS1 →	+0.745	+0.347	<.001	<.001	3	5
UCEC	GPR161 →	+0.757	+0.378	.005	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,437 associations by consensus.

ITPKB vs RGMA — LSCC

Explore this scatter interactively →