ITPKB-AS1

Across TCGA pan-cancer cohorts, ITPKB-AS1 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated ITPKB-AS1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ITPKB-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ITPKB-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and STAD show a favorable association.

HNSC, LUSC, and STAD are the cancer types where ITPKB-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.690	0.574	.009	57	view →
LUSC	OS	Tertile	IV	0.001	0.673	.014	36	view →
STAD	DFS	Tertile	III,IV	0.697	0.444	.009	34	view →
UCS	OS	Tertile	II,III,IV	0.851	0.510	.021	30	view →
MESO	OS	Tertile	All	0.572	0.320	.005	27	view →
LIHC	DFS	Tertile	All	0.704	0.521	.007	27	view →
KIRP	DFS	Tertile	All	0.740	0.887	.005	21	view →
LGG	OS	Quartile	All	0.677	0.840	.003	13	view →
LAML	DFS	Quartile	All	0.621	0.286	.011	12	view →
DLBC	DFS	Median	III,IV	1.000	0.525	.013	7	view →
SARC	DFS	Quartile	All	0.721	0.552	.016	7	view →
OV	OS	Quartile	IV	0.219	0.429	.026	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

ITPKB-AS1–HNSC (DFS)

Open the HNSC breakdown →