ITPKB-AS1

Across TCGA pan-cancer cohorts, ITPKB-AS1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of ITPKB-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where ITPKB-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types ITPKB-AS1 is over-expressed in tumor, although a few such as UCEC and READ show the opposite, repressed pattern.

UCEC, READ, and COAD are the cancer types where ITPKB-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ITPKB-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	IV	−0.590	.002	8	view →
READ	Male	All	−0.143	.001	4	view →
COAD	All	II,III,IV	−0.064	<.001	4	view →
LUSC	Female	All	−0.082	.046	1	view →
KICH	Male	All	−0.061	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

ITPKB-AS1–UCEC

Open the UCEC breakdown →