ITPKA

Across TCGA patient cohorts, ITPKA protein abundance is significantly associated with the RNA expression of many other genes, with 13,520 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ITPKA-associated genes across cancer lineages are SERPINB1, ACADS, and NWD2. Each is linked with ITPKA in more than 2 cancer types. Because this analysis shows association rather than direction, both ITPKA-to-partner and partner-to-ITPKA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITPKA versus SERPINB1 in BRCA, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITPKA→partner) and Y-score (partner→ITPKA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SERPINB1 →	+1.157	+1.296	<.001	<.001	3	3
BRCA	ACADS →	+1.579	+0.955	<.001	<.001	3	2
GBM	NWD2 →	+0.572	+0.302	<.001	<.001	3	2
GBM	LINC00200 →	+0.165	+0.420	<.001	<.001	3	2
LUAD	LTK →	+1.536	+0.805	<.001	<.001	3	2
LUAD	PCSK1N →	-2.377	-0.754	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,520 associations by consensus.

ITPKA vs SERPINB1 — BRCA

Explore this scatter interactively →