ITPK1

Across TCGA patient cohorts, ITPK1 protein abundance is significantly associated with the RNA expression of many other genes, with 23,063 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ITPK1-associated genes across cancer lineages are CALM1, GON7, and TMEM251. Each is linked with ITPK1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ITPK1-to-partner and partner-to-ITPK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITPK1 versus CALM1 in GBM, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITPK1→partner) and Y-score (partner→ITPK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CALM1 →	+0.465	+0.273	<.001	<.001	3	6
OV	GON7 →	+0.661	+0.367	<.001	<.001	3	5
BRCA	TMEM251 →	+0.506	+0.405	<.001	<.001	3	5
BRCA	SETD3 →	+0.428	+0.325	<.001	<.001	3	5
HNSC	ST8SIA1 →	-0.909	-0.268	<.001	.002	3	4
OV	GSKIP →	+0.438	+0.238	.001	.009	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,063 associations by consensus.

ITPK1 vs CALM1 — GBM

Explore this scatter interactively →