ITM2B

Across TCGA patient cohorts, ITM2B RNA expression is significantly associated with the protein abundance of many other proteins, with 15,570 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ITM2B-associated proteins across cancer lineages are RFC1_S368, LMNA, and PPFIBP1. Each is linked with ITM2B in more than 5 cancer types. Because this analysis shows association rather than direction, both ITM2B-to-partner and partner-to-ITM2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITM2B versus RFC1_S368 in GBM, with a Pearson correlation of -0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ITM2B→partner) and Y-score (partner→ITM2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RFC1_S368 →	-0.792	-0.589	<.001	<.001	3	6
UCEC	LMNA →	+0.444	+0.559	.008	.003	3	6
BRCA	PPFIBP1 →	+0.344	+0.448	<.001	<.001	3	6
BRCA	SSH3 →	+0.440	+0.496	<.001	<.001	3	6
GBM	NASP →	-0.725	-0.761	<.001	<.001	3	6
GBM	NCAPD2 →	-0.775	-0.652	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,570 associations by consensus.

ITM2B vs RFC1_S368 — GBM

Explore this scatter interactively →