ITM2A

Across TCGA cell cohorts, ITM2A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,769 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ITM2A-associated GO terms across cancer lineages are Purine nucleoside triphosphate biosynthetic process, Ribonucleoside triphosphate biosynthetic process, and Purine ribonucleoside triphosphate biosynthetic process. Each is linked with ITM2A in more than 7 cancer types. Because this analysis shows association rather than direction, both ITM2A-to-partner and partner-to-ITM2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Purine nucleoside triphosphate biosynthetic process grouped by ITM2A-low versus ITM2A-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ITM2A→partner) and Y-score (partner→ITM2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Purine nucleoside triphosphate biosynthetic process →	+0.057	+2.644	.005	.005	3	7
BLOOD_Leukemia	Ribonucleoside triphosphate biosynthetic process →	+0.053	+2.811	.003	.002	2	8
BLOOD_Leukemia	Purine ribonucleoside triphosphate biosynthetic process →	+0.057	+2.644	.005	.005	3	7
PANCREAS	Positive regulation of organelle assembly →	+0.044	+0.766	<.001	.004	3	6
BLOOD_Lymphoma	Positive regulation of attachment of mitotic spindle microtubules to kinetochore →	+0.081	+1.807	.004	.009	3	6
BONE	Sensory perception of light stimulus →	-0.050	-4.562	.002	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,769 associations by consensus.

Purine nucleoside triphosphate biosynthetic process by ITM2A expression — BLOOD_Leukemia

Explore this box plot interactively →