ITIH5

Across TCGA patient cohorts, ITIH5 protein abundance is significantly associated with the RNA expression of many other genes, with 13,309 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ITIH5-associated genes across cancer lineages are FHL5, CLEC14A, and GPIHBP1. Each is linked with ITIH5 in more than 7 cancer types. Because this analysis shows association rather than direction, both ITIH5-to-partner and partner-to-ITIH5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITIH5 versus FHL5 in LUAD, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITIH5→partner) and Y-score (partner→ITIH5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FHL5 →	+0.805	+0.428	<.001	<.001	3	8
UCEC	CLEC14A →	+0.661	+0.485	<.001	<.001	3	8
LSCC	GPIHBP1 →	+0.961	+0.466	<.001	<.001	3	8
BRCA	COX7A1 →	+1.346	+0.779	<.001	<.001	3	8
LUAD	ZBTB16 →	+1.691	+0.461	<.001	<.001	3	7
BRCA	MMRN1 →	+1.596	+0.879	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,309 associations by consensus.

ITIH5 vs FHL5 — LUAD

Explore this scatter interactively →