ITIH3

Across TCGA patient cohorts, ITIH3 RNA expression is significantly associated with the protein abundance of many other proteins, with 23,341 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ITIH3-associated proteins across cancer lineages are PPP1R12B, CNRIP1, and DDX21_S121. Each is linked with ITIH3 in more than 7 cancer types. Because this analysis shows association rather than direction, both ITIH3-to-partner and partner-to-ITIH3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITIH3 versus PPP1R12B in COAD, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ITIH3→partner) and Y-score (partner→ITIH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PPP1R12B →	+0.625	+0.227	<.001	<.001	3	8
COAD	CNRIP1 →	+0.597	+0.429	<.001	<.001	3	8
BRCA	DDX21_S121 →	-0.813	-0.373	<.001	<.001	3	8
BRCA	OLFML1 →	+0.730	+0.376	<.001	<.001	3	7
COAD	PALM →	+0.574	+0.306	<.001	<.001	3	7
BRCA	SSC5D →	+0.768	+0.379	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,341 associations by consensus.

ITIH3 vs PPP1R12B — COAD

Explore this scatter interactively →