ITIH3

Across TCGA patient cohorts, ITIH3 protein abundance is significantly associated with the RNA expression of many other genes, with 11,113 significant associations in total. COAD shows the largest number of these associations.

The most reproducible ITIH3-associated genes across cancer lineages are TNFAIP6, LRRC32, and CD93. Each is linked with ITIH3 in more than 7 cancer types. Because this analysis shows association rather than direction, both ITIH3-to-partner and partner-to-ITIH3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITIH3 versus TNFAIP6 in OV, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITIH3→partner) and Y-score (partner→ITIH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TNFAIP6 →	+1.017	+0.663	.006	.001	3	8
OV	LRRC32 →	+0.865	+0.683	.001	<.001	3	8
CCRCC	CD93 →	+0.877	+0.609	<.001	<.001	3	8
OV	LYVE1 →	+1.052	+0.678	.001	<.001	3	8
COAD	P4HA3 →	+0.949	+0.758	<.001	<.001	3	7
BRCA	SHROOM4 →	+0.616	+0.751	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,113 associations by consensus.

ITIH3 vs TNFAIP6 — OV

Explore this scatter interactively →