ITIH3

Across TCGA cell cohorts, ITIH3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,495 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ITIH3-associated GO terms across cancer lineages are Cell division, Cytoskeleton-dependent cytokinesis, and Cytokinesis. Each is linked with ITIH3 in more than 5 cancer types. Because this analysis shows association rather than direction, both ITIH3-to-partner and partner-to-ITIH3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell division grouped by ITIH3-low versus ITIH3-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ITIH3→partner) and Y-score (partner→ITIH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Cell division →	+0.064	+0.182	<.001	.001	3	6
BREAST	Cytoskeleton-dependent cytokinesis →	+0.057	+0.158	<.001	.006	3	6
BREAST	Cytokinesis →	+0.058	+0.158	<.001	.006	3	6
SKIN	Vacuole organization →	+0.048	+0.905	<.001	.001	3	6
BLOOD_Myeloma	Detection of external stimulus →	-0.055	-0.500	.004	.001	2	6
BLOOD_Myeloma	tRNA transcription by RNA polymerase III →	+0.058	+0.352	.002	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,495 associations by consensus.

Cell division by ITIH3 expression — BREAST

Explore this box plot interactively →