ITIH2

Across TCGA patient cohorts, ITIH2 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,496 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ITIH2-associated proteins across cancer lineages are PLAC9, REXO4, and REXO4_S111. Each is linked with ITIH2 in more than 3 cancer types. Because this analysis shows association rather than direction, both ITIH2-to-partner and partner-to-ITIH2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITIH2 versus PLAC9 in GBM, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ITIH2→partner) and Y-score (partner→ITIH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PLAC9 →	+0.581	+0.744	<.001	.001	3	4
LSCC	REXO4 →	-0.427	-0.293	<.001	.007	3	3
LSCC	REXO4_S111 →	-0.829	-0.372	<.001	.001	3	3
GBM	RGS3 →	+0.379	+0.804	.003	.009	3	3
HNSC	HAAO →	+0.305	+0.426	.001	<.001	3	3
BRCA	IQGAP2_S685 →	+0.678	+0.480	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,496 associations by consensus.

ITIH2 vs PLAC9 — GBM

Explore this scatter interactively →