ITGB6

Across TCGA patient cohorts, ITGB6 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,150 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ITGB6-associated proteins across cancer lineages are ITGAV, ITGB6_S765, and LAMC2. Each is linked with ITGB6 in more than 5 cancer types. Because this analysis shows association rather than direction, both ITGB6-to-partner and partner-to-ITGB6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGB6 versus ITGAV in LSCC, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGB6→partner) and Y-score (partner→ITGB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ITGAV →	+0.544	+1.412	<.001	<.001	3	6
LSCC	ITGB6_S765 →	+1.948	+2.022	<.001	<.001	3	6
HNSC	LAMC2 →	+1.096	+1.218	<.001	<.001	3	6
BRCA	ZYX →	+0.489	+2.159	<.001	<.001	3	5
LSCC	UNG →	-0.466	-1.055	<.001	<.001	3	5
BRCA	PDLIM7 →	+0.705	+1.891	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,150 associations by consensus.

ITGB6 vs ITGAV — LSCC

Explore this scatter interactively →