ITGB3BP

Across TCGA pan-cancer cohorts, ITGB3BP Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ITGB3BP data layer compared with 27 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher ITGB3BP Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ITGB3BP expression acts as an unfavorable survival marker.

LIHC, UCEC, and PRAD are the cancer types where ITGB3BP Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	All	0.226	0.773	.008	12	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ITGB3BP–LIHC (OS)

Open the LIHC breakdown →