ITGB3

Across TCGA patient cohorts, ITGB3 RNA expression is significantly associated with the RNA expression of many other genes, with 18,972 significant associations in total. THYM shows the largest number of these associations.

The most reproducible ITGB3-associated genes across cancer lineages are ASXL2, VCL, and MYLK. Each is linked with ITGB3 in more than 33 cancer types. Because this analysis shows association rather than direction, both ITGB3-to-partner and partner-to-ITGB3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGB3 versus ASXL2 in UVM, with a Pearson correlation of 0.51.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGB3→partner) and Y-score (partner→ITGB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	ASXL2 →	+1.113	+0.418	<.001	<.001	3	34
PRAD	VCL →	+1.500	+1.061	<.001	<.001	3	34
SARC	MYLK →	+2.987	+1.217	<.001	<.001	3	33
DLBC	EP300 →	+1.436	+0.783	<.001	<.001	3	33
UVM	SEC23A →	+1.200	+0.383	<.001	<.001	3	33
ACC	PRKAR1A →	+1.193	+0.337	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,972 associations by consensus.

ITGB3 vs ASXL2 — UVM

Explore this scatter interactively →