ITGB1BP2

Across TCGA cell cohorts, ITGB1BP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,762 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ITGB1BP2-associated GO terms across cancer lineages are Telomeric loop disassembly, DNA replication proofreading, and Mitotic DNA integrity checkpoint signaling. Each is linked with ITGB1BP2 in more than 15 cancer types. Because this analysis shows association rather than direction, both ITGB1BP2-to-partner and partner-to-ITGB1BP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomeric loop disassembly grouped by ITGB1BP2-low versus ITGB1BP2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGB1BP2→partner) and Y-score (partner→ITGB1BP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Telomeric loop disassembly →	+0.154	+0.926	.001	<.001	3	16
SKIN	DNA replication proofreading →	+0.151	+0.544	<.001	<.001	3	15
BONE	Mitotic DNA integrity checkpoint signaling →	+0.095	+0.628	.008	.001	3	15
BONE	Telomere maintenance →	+0.085	+0.823	.003	.006	3	15
BREAST	Centriole assembly →	+0.070	+0.506	.002	.007	2	16
BLOOD_Myeloma	Centriole replication →	+0.087	+0.753	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,762 associations by consensus.

Telomeric loop disassembly by ITGB1BP2 expression — BONE

Explore this box plot interactively →