ITGB1BP1

Across TCGA pan-cancer cohorts, ITGB1BP1 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ITGB1BP1 data layer compared with 26 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher ITGB1BP1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated ITGB1BP1 expression acts as an unfavorable survival marker.

BRCA and SKCM are the cancer types where ITGB1BP1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Median	All	0.153	0.526	.036	4	view →
SKCM	DFS	Median	III,IV	0.015	0.648	<.001	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

ITGB1BP1–BRCA (DFS)

Open the BRCA breakdown →