ITGB1BP1

Across TCGA pan-cancer cohorts, ITGB1BP1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ITGB1BP1 data layer compared with 26 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher ITGB1BP1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated ITGB1BP1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and HNSC show a favorable association.

LSCC, HNSC, and LUAD are the cancer types where ITGB1BP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Tertile	All	0.947	0.739	.004	28	view →
HNSC	OS	Quartile	All	1.000	0.259	.036	8	view →
LUAD	OS	Median	II,III,IV	0.303	0.832	.003	6	view →
CCRCC	OS	Quartile	All	0.865	1.000	.023	5	view →
GBM	DFS	Median	All	0.821	0.620	<.001	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ITGB1BP1–LSCC (OS)

Open the LSCC breakdown →