ITGB1BP1

Across TCGA cell cohorts, ITGB1BP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,298 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ITGB1BP1-associated GO terms across cancer lineages are Regulation of mitotic sister chromatid separation, Negative regulation of mitotic sister chromatid separation, and Negative regulation of sister chromatid segregation. Each is linked with ITGB1BP1 in more than 12 cancer types. Because this analysis shows association rather than direction, both ITGB1BP1-to-partner and partner-to-ITGB1BP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitotic sister chromatid separation grouped by ITGB1BP1-low versus ITGB1BP1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGB1BP1→partner) and Y-score (partner→ITGB1BP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of mitotic sister chromatid separation →	+0.165	+0.896	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mitotic sister chromatid separation →	+0.168	+0.822	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Negative regulation of sister chromatid segregation →	+0.168	+0.822	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mitotic sister chromatid segregation →	+0.168	+0.822	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mitotic metaphase/anaphase transition →	+0.168	+0.822	<.001	<.001	3	13
OESOPHAGUS	Centromeric sister chromatid cohesion →	+0.219	+1.180	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,298 associations by consensus.

Regulation of mitotic sister chromatid separation by ITGB1BP1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →