ITGB1BP1

Across TCGA cell cohorts, ITGB1BP1 mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ITGB1BP1-associated genes across cancer lineages are PPP1R2C, TAS2R7, and FTHL17. Each is linked with ITGB1BP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ITGB1BP1-to-partner and partner-to-ITGB1BP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PPP1R2C grouped by ITGB1BP1-low versus ITGB1BP1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGB1BP1→partner) and Y-score (partner→ITGB1BP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	PPP1R2C →	+0.456	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	TAS2R7 →	+0.042	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	FTHL17 →	+0.239	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	PLCZ1 →	+0.169	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	WFDC8 →	+0.022	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	OR8B12 →	+0.139	+6.247	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

PPP1R2C by ITGB1BP1 expression — BLOOD_Lymphoma

Explore this box plot interactively →