ITGAV

Across TCGA cell cohorts, ITGAV RNA expression is significantly associated with the go_rna of many other GO terms, with 6,301 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ITGAV-associated GO terms across cancer lineages are Negative regulation of lipoprotein metabolic process, Positive regulation of osteoblast proliferation, and Wound healing, spreading of cells. Each is linked with ITGAV in more than 18 cancer types. Because this analysis shows association rather than direction, both ITGAV-to-partner and partner-to-ITGAV results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of lipoprotein metabolic process grouped by ITGAV-low versus ITGAV-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGAV→partner) and Y-score (partner→ITGAV) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Negative regulation of lipoprotein metabolic process →	+1.421	+1.704	<.001	<.001	3	19
LUNG_SCLC	Positive regulation of osteoblast proliferation →	+1.511	+1.549	<.001	<.001	3	17
BONE	Wound healing, spreading of cells →	+0.171	+1.721	<.001	<.001	3	16
BONE	Epiboly involved in wound healing →	+0.171	+1.721	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Regulation of entry of bacterium into host cell →	+0.269	+1.842	.001	.001	3	15
BONE	Biological process involved in symbiotic interaction →	+0.134	+2.695	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,301 associations by consensus.

Negative regulation of lipoprotein metabolic process by ITGAV expression — BLOOD_Myeloma

Explore this box plot interactively →