ITGAM

Across TCGA patient cohorts, ITGAM RNA expression is significantly associated with the protein abundance of many other proteins, with 22,548 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ITGAM-associated proteins across cancer lineages are APBB1IP, MYO1F, and ARHGAP25. Each is linked with ITGAM in more than 9 cancer types. Because this analysis shows association rather than direction, both ITGAM-to-partner and partner-to-ITGAM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGAM versus APBB1IP in OV, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGAM→partner) and Y-score (partner→ITGAM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	APBB1IP →	+0.827	+1.588	<.001	<.001	3	10
GBM	MYO1F →	+0.865	+1.175	<.001	<.001	3	10
OV	ARHGAP25 →	+1.036	+2.132	.009	.001	3	10
GBM	ARHGAP30 →	+0.798	+1.180	<.001	<.001	3	10
GBM	PTPN6 →	+0.844	+1.124	<.001	<.001	3	10
GBM	ARHGAP45 →	+0.755	+1.073	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,548 associations by consensus.

ITGAM vs APBB1IP — OV

Explore this scatter interactively →