ITGAE

Across TCGA cell cohorts, ITGAE RNA expression is significantly associated with the RNA expression of many other genes, with 9,491 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ITGAE-associated genes across cancer lineages are PSMB6, MED31, and COPS3. Each is linked with ITGAE in more than 15 cancer types. Because this analysis shows association rather than direction, both ITGAE-to-partner and partner-to-ITGAE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGAE versus PSMB6 in LUNG_NSCLC_LUSC, with a Pearson correlation of 0.91.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGAE→partner) and Y-score (partner→ITGAE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	PSMB6 →	+1.468	+1.494	<.001	<.001	3	16
LUNG_NSCLC_LUSC	MED31 →	+0.924	+0.883	.001	.003	2	15
UPPER_AERODIGESTIVE_TRACT	COPS3 →	+0.965	+1.073	<.001	<.001	3	14
URINARY_TRACT	MIS12 →	+0.912	+1.056	.001	.003	2	15
LUNG_NSCLC_LUSC	SLC25A11 →	+0.945	+1.027	<.001	.006	3	14
OESOPHAGUS	TIMM22 →	+0.928	+0.920	<.001	.002	2	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,491 associations by consensus.

ITGAE vs PSMB6 — LUNG_NSCLC_LUSC

Explore this scatter interactively →