ITGA5

Across TCGA patient cohorts, ITGA5 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,077 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ITGA5-associated proteins across cancer lineages are C1S, COL3A1, and CRTAP. Each is linked with ITGA5 in more than 9 cancer types. Because this analysis shows association rather than direction, both ITGA5-to-partner and partner-to-ITGA5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGA5 versus C1S in OV, with a Pearson correlation of 0.77.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGA5→partner) and Y-score (partner→ITGA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	C1S →	+0.837	+1.395	<.001	<.001	3	10
GBM	COL3A1 →	+1.015	+1.097	<.001	<.001	3	10
OV	CRTAP →	+0.668	+1.358	<.001	<.001	3	10
GBM	P3H1 →	+0.691	+1.110	<.001	<.001	3	10
OV	TNC →	+1.258	+1.675	<.001	<.001	3	10
OV	FN1 →	+1.279	+1.402	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,077 associations by consensus.

ITGA5 vs C1S — OV

Explore this scatter interactively →