ITGA5

Across TCGA patient cohorts, ITGA5 protein abundance is significantly associated with the RNA expression of many other genes, with 19,368 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ITGA5-associated genes across cancer lineages are GFPT2, SPOCD1, and ADAMTS12. Each is linked with ITGA5 in more than 9 cancer types. Because this analysis shows association rather than direction, both ITGA5-to-partner and partner-to-ITGA5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGA5 versus GFPT2 in CCRCC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGA5→partner) and Y-score (partner→ITGA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	GFPT2 →	+1.314	+0.369	<.001	<.001	3	10
GBM	SPOCD1 →	+1.580	+0.483	<.001	<.001	3	10
OV	ADAMTS12 →	+1.438	+0.651	<.001	<.001	3	10
OV	FBXO32 →	+1.433	+0.598	.001	.001	3	10
HNSC	LGALS1 →	+1.604	+0.406	<.001	<.001	3	9
COAD	MYL9 →	+1.390	+0.597	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,368 associations by consensus.

ITGA5 vs GFPT2 — CCRCC

Explore this scatter interactively →