ITGA4

Across TCGA patient cohorts, ITGA4 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,051 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ITGA4-associated proteins across cancer lineages are WIPF1, ITGA4_S1021, and LCP2. Each is linked with ITGA4 in more than 9 cancer types. Because this analysis shows association rather than direction, both ITGA4-to-partner and partner-to-ITGA4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGA4 versus WIPF1 in OV, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGA4→partner) and Y-score (partner→ITGA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	WIPF1 →	+0.485	+0.757	<.001	<.001	3	10
GBM	ITGA4_S1021 →	+1.062	+1.096	<.001	<.001	3	10
GBM	LCP2 →	+0.602	+1.059	<.001	<.001	3	10
GBM	LPXN →	+0.568	+0.609	<.001	<.001	3	10
GBM	PLEKHO2 →	+0.452	+1.070	<.001	<.001	3	9
BRCA	ARHGEF6 →	+0.481	+0.759	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,051 associations by consensus.

ITGA4 vs WIPF1 — OV

Explore this scatter interactively →