ITGA4

Across TCGA cell cohorts, ITGA4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,996 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ITGA4-associated GO terms across cancer lineages are Diapedesis, Immune response in gut-associated lymphoid tissue, and Cytokinesis. Each is linked with ITGA4 in more than 12 cancer types. Because this analysis shows association rather than direction, both ITGA4-to-partner and partner-to-ITGA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Diapedesis grouped by ITGA4-low versus ITGA4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGA4→partner) and Y-score (partner→ITGA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Diapedesis →	+1.308	+2.395	<.001	<.001	3	13
SKIN	Immune response in gut-associated lymphoid tissue →	+1.805	+3.513	<.001	<.001	3	12
BREAST	Cytokinesis →	+0.085	+1.493	<.001	.001	3	10
OESOPHAGUS	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.122	+1.887	<.001	.003	3	10
OESOPHAGUS	Nuclear export →	+0.075	+1.354	.002	.002	3	10
BREAST	Nucleus organization →	+0.071	+1.687	<.001	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,996 associations by consensus.

Diapedesis by ITGA4 expression — BONE

Explore this box plot interactively →