ITGA2

Across TCGA patient cohorts, ITGA2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,745 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ITGA2-associated genes across cancer lineages are TGIF1, CPVL, and DKK1. Each is linked with ITGA2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ITGA2-to-partner and partner-to-ITGA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGA2 versus TGIF1 in HNSC, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGA2→partner) and Y-score (partner→ITGA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TGIF1 →	+0.774	+0.576	<.001	<.001	3	5
UCEC	CPVL →	-0.862	-0.725	.003	<.001	3	4
UCEC	DKK1 →	+2.740	+0.724	<.001	<.001	2	5
UCEC	SPRY2 →	+1.179	+0.879	<.001	<.001	3	4
CCRCC	IER3 →	+1.158	+0.468	<.001	<.001	3	4
UCEC	GALM →	-1.019	-0.654	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,745 associations by consensus.

ITGA2 vs TGIF1 — HNSC

Explore this scatter interactively →