ITGA10

Across TCGA pan-cancer cohorts, ITGA10 Mutation is linked to patient survival in 8 of 34 cancer types, making it a survival-associated ITGA10 data layer compared with 28 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ITGA10 Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated ITGA10 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, BLCA, and HNSC are the cancer types where ITGA10 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.970	0.827	.016	14	view →
BLCA	OS	Median	IV	0.089	0.599	<.001	12	view →
HNSC	DFS	Median	II,III,IV	0.087	0.695	<.001	12	view →
COAD	OS	Median	III,IV	0.266	0.705	.010	9	view →
BRCA	OS	Median	All	0.235	0.580	.015	7	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
ACC	OS	Median	All	0.118	0.624	.038	6	view →
LUAD	OS	Median	All	0.307	0.673	.030	6	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

ITGA10–UCEC (DFS)

Open the UCEC breakdown →