ITFG2

Across TCGA patient cohorts, ITFG2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,676 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ITFG2-associated proteins across cancer lineages are GTF2I, HNRNPU, and SIN3A. Each is linked with ITFG2 in more than 6 cancer types. Because this analysis shows association rather than direction, both ITFG2-to-partner and partner-to-ITFG2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITFG2 versus GTF2I in GBM, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ITFG2→partner) and Y-score (partner→ITFG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GTF2I →	+0.489	+0.350	<.001	<.001	3	7
GBM	HNRNPU →	+0.291	+0.337	<.001	<.001	3	7
GBM	SIN3A →	+0.280	+0.258	.002	.001	3	6
HNSC	ADNP →	+0.281	+0.519	<.001	<.001	3	6
UCEC	CXXC1 →	+0.232	+0.380	<.001	.003	3	6
GBM	HCFC1 →	+0.293	+0.373	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,676 associations by consensus.

ITFG2 vs GTF2I — GBM

Explore this scatter interactively →