ITCH-AS1

Across TCGA patient cohorts, ITCH-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 6,442 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ITCH-AS1-associated proteins across cancer lineages are PRCC_S157, MIA2_S1243, and ITCH. Each is linked with ITCH-AS1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ITCH-AS1-to-partner and partner-to-ITCH-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITCH-AS1 versus PRCC_S157 in LUAD, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ITCH-AS1→partner) and Y-score (partner→ITCH-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PRCC_S157 →	+0.519	+0.367	<.001	.005	3	3
LUAD	MIA2_S1243 →	-0.827	-0.423	<.001	.003	3	3
LSCC	ITCH →	+0.171	+0.383	<.001	<.001	3	3
GBM	SIN3B_S740 →	+0.434	+0.535	.001	<.001	3	3
OV	CCN1 →	+0.575	+0.172	.004	.005	3	3
LSCC	ITCH_S221 →	+0.346	+0.429	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,442 associations by consensus.

ITCH-AS1 vs PRCC_S157 — LUAD

Explore this scatter interactively →