ITCH-AS1

Across TCGA patient cohorts, ITCH-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,466 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ITCH-AS1-associated GO terms across cancer lineages are Methylation, Positive regulation of DNA metabolic process, and Obsolete ncRNA export from nucleus. Each is linked with ITCH-AS1 in more than 18 cancer types. Because this analysis shows association rather than direction, both ITCH-AS1-to-partner and partner-to-ITCH-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Methylation grouped by ITCH-AS1-low versus ITCH-AS1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ITCH-AS1→partner) and Y-score (partner→ITCH-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Methylation →	+0.055	+0.536	<.001	<.001	3	19
STAD	Positive regulation of DNA metabolic process →	+0.064	+0.495	<.001	<.001	3	19
STAD	Obsolete ncRNA export from nucleus →	+0.063	+0.404	<.001	<.001	3	19
STAD	Regulation of RNA splicing →	+0.074	+0.481	<.001	<.001	3	19
STAD	Regulation of transcription elongation by RNA polymerase II →	+0.064	+0.428	<.001	<.001	3	18
STAD	Regulation of mRNA splicing, via spliceosome →	+0.075	+0.490	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,466 associations by consensus.

Methylation by ITCH-AS1 expression — STAD

Explore this box plot interactively →