ISL2

Across TCGA patient cohorts, ISL2 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ISL2-associated genes across cancer lineages are Adipocytes and Erythrocytes. Each is linked with ISL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ISL2-to-partner and partner-to-ISL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adipocytes grouped by ISL2-low versus ISL2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ISL2→partner) and Y-score (partner→ISL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Adipocytes →	+0.023	+2.144	.009	.036	3	1
UCEC	Erythrocytes →	+0.029	+2.241	.017	.031	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Adipocytes by ISL2 expression — UCEC

Explore this box plot interactively →