ISCA1P3

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, ISCA1P3 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of ISCA1P3’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where ISCA1P3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ISCA1P3 is over-expressed in tumor.

BRCA are the cancer types where ISCA1P3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ISCA1P3 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
BRCAAllII,III,IV+0.021.0341view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

ISCA1P3–BRCA

Tumor-vs-normal expression box plot for ISCA1P3 RNA in BRCA.

Open the BRCA breakdown →

Exploration