IRX5

Across TCGA patient cohorts, IRX5 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,586 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IRX5-associated proteins across cancer lineages are IRX5_T237, IRX5_S185, and SORD. Each is linked with IRX5 in more than 5 cancer types. Because this analysis shows association rather than direction, both IRX5-to-partner and partner-to-IRX5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IRX5 versus IRX5_T237 in UCEC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IRX5→partner) and Y-score (partner→IRX5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IRX5_T237 →	+1.326	+1.463	.003	<.001	3	6
CCRCC	IRX5_S185 →	+1.584	+1.791	<.001	<.001	3	5
BRCA	SORD →	+0.453	+0.842	<.001	<.001	3	5
BRCA	GBP5 →	-0.822	-0.807	<.001	.006	3	5
HNSC	GIMAP8 →	-0.408	-0.602	.002	.003	2	6
CCRCC	IRX5_S464 →	+1.342	+1.589	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,586 associations by consensus.

IRX5 vs IRX5_T237 — UCEC

Explore this scatter interactively →