IRF5P1

Across TCGA patient cohorts, IRF5P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,375 significant associations in total. STAD shows the largest number of these associations.

The most reproducible IRF5P1-associated GO terms across cancer lineages are RNA methylation, Negative regulation of protein catabolic process, and Protein targeting to membrane. Each is linked with IRF5P1 in more than 12 cancer types. Because this analysis shows association rather than direction, both IRF5P1-to-partner and partner-to-IRF5P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA methylation grouped by IRF5P1-low versus IRF5P1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IRF5P1→partner) and Y-score (partner→IRF5P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RNA methylation →	+0.088	+0.044	<.001	<.001	3	13
STAD	Negative regulation of protein catabolic process →	+0.094	+0.049	<.001	<.001	3	13
STAD	Protein targeting to membrane →	+0.090	+0.044	<.001	<.001	3	12
STAD	Telomere maintenance →	+0.097	+0.047	<.001	<.001	3	12
STAD	Telomere organization →	+0.092	+0.044	<.001	<.001	3	12
STAD	Methylation →	+0.089	+0.053	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,375 associations by consensus.

RNA methylation by IRF5P1 expression — STAD

Explore this box plot interactively →