IRF5P1

Across TCGA pan-cancer cohorts, IRF5P1 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated IRF5P1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher IRF5P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated IRF5P1 expression acts as an unfavorable survival marker.

KIRC, KICH, and LIHC are the cancer types where IRF5P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.394	0.646	<.001	93	view →
KICH	DFS	Tertile	All	0.372	0.922	<.001	72	view →
LIHC	OS	Tertile	III,IV	0.051	0.616	<.001	27	view →
BLCA	OS	Tertile	IV	0.153	0.587	.011	18	view →
LUAD	OS	Tertile	II,III,IV	0.368	0.761	.007	18	view →
UVM	OS	Tertile	All	0.353	0.724	.019	12	view →
PAAD	DFS	Tertile	II,III,IV	0.143	0.477	.005	9	view →
PCPG	OS	Tertile	All	0.078	0.953	.035	9	view →
ACC	OS	Tertile	All	0.149	0.686	.047	9	view →
KIRP	OS	Tertile	III,IV	0.180	0.688	.027	9	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

IRF5P1–KIRC (DFS)

Open the KIRC breakdown →