IRF5

Across TCGA patient cohorts, IRF5 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,828 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IRF5-associated proteins across cancer lineages are APOBR, MYO1G, and NCF2. Each is linked with IRF5 in more than 6 cancer types. Because this analysis shows association rather than direction, both IRF5-to-partner and partner-to-IRF5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IRF5 versus APOBR in UCEC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IRF5→partner) and Y-score (partner→IRF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	APOBR →	+0.666	+0.992	<.001	<.001	3	7
GBM	MYO1G →	+0.625	+0.637	<.001	<.001	3	7
UCEC	NCF2 →	+0.836	+0.962	<.001	<.001	3	7
GBM	PARVG →	+0.741	+0.781	<.001	<.001	3	7
GBM	VAV1 →	+0.773	+0.873	<.001	<.001	3	7
UCEC	CARD11 →	+0.581	+1.141	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,828 associations by consensus.

IRF5 vs APOBR — UCEC

Explore this scatter interactively →