Across TCGA patient cohorts, IRF1-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,808 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IRF1-AS1-associated proteins across cancer lineages are UBA7, IFIT5, and PSMB6. Each is linked with IRF1-AS1 in more than 7 cancer types. Because this analysis shows association rather than direction, both IRF1-AS1-to-partner and partner-to-IRF1-AS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IRF1-AS1→partner) and Y-score (partner→IRF1-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	UBA7 →	+0.487	+1.033	<.001	<.001	3	8
HNSC	IFIT5 →	+0.371	+0.561	<.001	<.001	3	8
HNSC	PSMB6 →	-0.418	-0.854	<.001	<.001	3	8
HNSC	SAMHD1 →	+0.557	+0.758	<.001	<.001	3	7
LUAD	TRIM22 →	+0.492	+0.671	<.001	<.001	3	7
HNSC	TRIM22_S87 →	+0.914	+0.876	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,808 associations by consensus.

Exploration

IRF1-AS1 survival (RNA) · tumor vs normal (RNA) · all IRF1-AS1 data types