IRF1-AS1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, IRF1-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,202 significant associations in total. BONE shows the largest number of these associations.

The most reproducible IRF1-AS1-associated GO terms across cancer lineages are Antigen processing and presentation of endogenous antigen, Antigen processing and presentation of exogenous peptide antigen via MHC class Ib, and Antigen processing and presentation of endogenous peptide antigen via MHC class I. Each is linked with IRF1-AS1 in more than 17 cancer types. Because this analysis shows association rather than direction, both IRF1-AS1-to-partner and partner-to-IRF1-AS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IRF1-AS1→partner) and Y-score (partner→IRF1-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUEAntigen processing and presentation of endogenous antigen →+0.307+1.459<.001<.001318
BONEAntigen processing and presentation of exogenous peptide antigen via MHC class Ib →+0.357+1.489<.001<.001318
SOFT_TISSUEAntigen processing and presentation of endogenous peptide antigen via MHC class I →+0.303+1.651<.001<.001317
SOFT_TISSUEAntigen processing and presentation of peptide antigen via MHC class I →+0.221+1.653<.001<.001316
LIVERCD8-positive, alpha-beta T cell homeostasis →+0.149+1.217.006.009315
BREASTRegulation of CD8-positive, alpha-beta T cell proliferation →+0.256+1.565<.001<.001315
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,202 associations by consensus.

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