IREB2

Across TCGA patient cohorts, IREB2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,179 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IREB2-associated proteins across cancer lineages are MORF4L1, RTF1, and SIN3A. Each is linked with IREB2 in more than 7 cancer types. Because this analysis shows association rather than direction, both IREB2-to-partner and partner-to-IREB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IREB2 versus MORF4L1 in LSCC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IREB2→partner) and Y-score (partner→IREB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MORF4L1 →	+0.328	+0.541	<.001	<.001	3	8
LSCC	RTF1 →	+0.316	+0.568	<.001	<.001	3	6
LSCC	SIN3A →	+0.231	+0.410	<.001	<.001	3	6
GBM	CTDSPL2 →	+0.338	+0.300	.004	.001	3	6
HNSC	GTF3C4 →	+0.313	+0.854	<.001	.002	3	6
LSCC	RBM39 →	+0.202	+0.467	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,179 associations by consensus.

IREB2 vs MORF4L1 — LSCC

Explore this scatter interactively →