IRAK2

Across TCGA patient cohorts, IRAK2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,017 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IRAK2-associated genes across cancer lineages are CHRM3-AS1, ACER1, and MYL9. Each is linked with IRAK2 in more than 2 cancer types. Because this analysis shows association rather than direction, both IRAK2-to-partner and partner-to-IRAK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IRAK2 versus CHRM3-AS1 in HNSC, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IRAK2→partner) and Y-score (partner→IRAK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CHRM3-AS1 →	-1.192	-0.574	.002	.005	3	3
HNSC	ACER1 →	+0.976	+0.643	<.001	<.001	3	2
LUAD	MYL9 →	-1.004	-0.603	<.001	.001	3	2
HNSC	PPFIBP1 →	-0.881	-0.698	.001	<.001	3	2
HNSC	PRRX1 →	-1.014	-0.457	.001	.005	3	2
LUAD	ST6GALNAC5 →	-1.250	-0.693	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,017 associations by consensus.

IRAK2 vs CHRM3-AS1 — HNSC

Explore this scatter interactively →