IRAG1

Across TCGA patient cohorts, IRAG1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,497 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible IRAG1-associated genes across cancer lineages are LMOD1, SYNPO2, and HSPB7. Each is linked with IRAG1 in more than 8 cancer types. Because this analysis shows association rather than direction, both IRAG1-to-partner and partner-to-IRAG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IRAG1 versus LMOD1 in CCRCC, with a Pearson correlation of 0.84.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IRAG1→partner) and Y-score (partner→IRAG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	LMOD1 →	+1.607	+0.692	<.001	<.001	3	9
CCRCC	SYNPO2 →	+1.461	+0.584	<.001	<.001	3	9
COAD	HSPB7 →	+1.164	+0.392	<.001	<.001	3	9
UCEC	DACT3 →	+0.922	+0.755	<.001	<.001	3	9
OV	MYLK →	+1.063	+0.686	.002	.001	3	9
OV	ACTA2 →	+1.681	+0.715	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,497 associations by consensus.

IRAG1 vs LMOD1 — CCRCC

Explore this scatter interactively →